RNA molecules display many different functions, from coding mRNAs, catalytic ribozymes to RNAs that regulate gene expression at all levels. I will present our attempts to identify regulatory RNAs that control their own transcription. Using genomic SELEX, we discovered a large number of RNA aptamers in E. coli, yeast and human genomes that function as cis-acting transcriptional silencers.
Session Chair: Prof. John Atkins, BioSciences Institute, University College Cork
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